Tufts Chemistry Department
Previous Seminar Speakers

Fall 2007

August 9	Prof. A. P. De Silva, Queen's University, Belfast "Messages from Molecules: Sensing and Computing" NOTE: This talk is on a Thursday at 4:30pm
August 20	Prof. Francisco Zaera, UC Riverside "The Mechanisms of Hydrocarbon Conversion Catalysis: Regioselectivity, Stereoselectivity, and Enantioselectivity" NOTE: This talk is on a Monday at 1:30pm
September 11	Dr. Rajaraman Krishnan, Whitehead Institute "Yeast prion structure: Nucleation and strain diversity"
September 18	Prof. Joanne Stubbe, MIT "Unnatural Amino Acids to probe the Radical Propagation Pathway of Ribonucleotide Reductase"
September 25	Prof. Weihong Tan, University of Florida "Molecular Profiling of Cancer: A Chemical Biology Approach"
October 2	Prof. Alex Kandel, Notre Dame "The role of local structure in surface chemistry "
October 9 CANCELLED	Prof. Wayne Goodman, Texas A&M "Catalysis by Au and Au Alloys: From Single Crystals to Nanoparticles"
October 18	Prof. Oliver Mullins, Schlumberger-Doll Research "Molecular Structure and Aggregation Structure of Asphaltenes"
October 23	Prof. Jonas Peters, MIT/CalTech "Multi-electron reactions with pseudotetrahedral transition metals"
October 30	Prof. Anne-Frances Miller, University of Kentucky "Redox Tuning Over Almost a Volt in a Conserved Structural Setting"
November 6	Dr. Sudip Parikh, Science Advisor - Senate Appropriations Committee "NIH Funding and Stem Cell Research: Mixing Science and Politics in the U.S. Senate"
November 13	Prof. Carolyn Bertozzi, UC Berkeley "Chemistry in Living Systems: Shedding Light on Glycans"

Spring 2007

January 30	Prof. Virginia Cornish, Columbia University Co-opting Nature’s Machineries for Chemical Discovery
February 06	Prof. Stephen Blacklow, Harvard Medical School Biochemical and Structural Foundations Underlying Notch Activation and Restraint
February 13	Max Tishler Award Lecture Prof. Steven Boxer, Stanford University Patterned Bilayers and Tethered Vesicles: Soft Nanoscience The Max Tishler Award Lecture will be held in P104, Pearson Chem on Tue, February 13th
February 20	Prof. John Koh, University of Delaware Chemical Rescue of Nuclear Receptor Mutations
February 27	Prof. Paul Barbara, University of Texas, Austin Single Molecule Spectroscopic Studies of Protein Nucleic Acid Interactions in the Reverse Transcription of HIV-1 in vitro
March 06	Prof. Ken Reid, University of Oxford Collectins - Proteins of Innate Immunity With Potential for Therapeutics for Infection and Inflammation
March 13	Prof. Arthur Veis, Northwestern University Collagen Molecular Assembly Mechanisms: The Key Role of Recognition Modules Within the Carboxyl Propeptide Domain In Chain Selectivity
March 27	Prof. Ashley Bush, Massachusetts General Hospital Copper and Zinc Interactions with β-Amyloid in Alzheimer’s Disease
April 10	Prof. Alanna Schepartz, Yale University Structure and Stability of Protein Devoid of Alpha Amino Acids
April 12	Prof. Robert H. Tykot, University of Southern Florida Stable Isotope Analysis of Human Remains to Study Ancient Diets in the New World
April 17	Prof. Richard Van Duyne, Northwestern University Molecular Plasmonics for Surface Enhanced Sensing and Raman Spectroscopy
April 18	Prof. Nikolaas van der Merwe, University of Cape Town, South Africa Light Stable Isotopes, the Diets of Early Hominins, and the Rain on the Serengeti Plain NOTE: This talk is on Wednesday at 12:30pm in P106
August 9	Prof. A.P. De Silva, Queen's University, Belfast Title TBA
August 20	Prof. Francisco Zaera, University of California at Riverside Title TBA NOTE: This talk is on a Monday
August 24	Prof. Franc Meyer, Georg-August-Universität Göttingen Title TBA NOTE: This talk is on a Friday

Fall 2006

September 12	Dr. Hans-Heiner Gorris, Westfälische Wilhelms–Universität, Münster Development of a High-throughput Proteolysis Assay and Analysis of the Proteolysis Resistance of Peptide Epitopes
September 19	Prof. Alice Ting, Massachusetts Institute of Technology New Chemical Reporters for Imaging Protein Function and Trafficking in Live Cells
September 26	Prof. Stewart Novick, Wesleyan University Laboratory Astrochemistry: The High Resolution Spectra of Radicals
October 03	Prof. Mark Hersam, Northwestern University Probing Chemistry and Electronic Structure at the Single Molecule Level with Scanning Tunneling Microscopy
October 10	Prof. Vladislav Sadtchenko, George Washington University Fast Thermal Desorption Spectroscopy Studies of Dynamics and Reactions in Ice
October 17	Prof. Geert-Jan Boons, University of Georgia A Fully Synthetic Three-Component Cancer Vaccine
October 24	Prof. Richard Johnson, University of New Hampshire Mechanisms of Fragmentation in Carbohydrate Mass Spectrometry and Other Tales of High Energy Molecules
October 31	Prof. Martin Case, University of Vermont Metal Directed Protein Assembly
November 17	Graduate Student Hosted Colloquium Prof. Harry Gray, California Institute of Technology The Currents of Life: Electron Flow Through Iron and Copper Proteins
December 05	Prof. Eric Anslyn, University of Texas, Austin Organic Chemistry Approaches to Single and Multi Analytes Sensing

Spring 2006

January 24	Prof. Annabella Selloni, Princeton University The Surface Science of TiO₂: Insights from First Principles Simulations
January 31	Dr. Timothy Clackson, Ariad Pharmaceuticals, Inc. Controlling Cellular Events Using Dimerizer Drugs
February 7	Prof. Steven Sibener, University of Chicago Interfacial Dynamics of Polymers and SAMs: Glassy Dynamics, Hierarchical Assembly, and the Quest for Perfection
February 23	Prof. Donald Hilvert, ETH Zürich, Switzerland Molecular Diversity and Catalysis
March 7	Prof. Andrew Gellman, Carnegie Mellon University Enantioselectivity on Naturally Chiral Surfaces
March 16	Max Tishler Award Lecture Prof. George Whitesides, Harvard University New Tools for Bioanalysis. The Development of Microsystems for Use in Cell and Molecular Biology The Max Tishler lecture will be held in P104, Pearson Chem on Thu, March 16th
March 30	Dr. Andrea Cochran, Genentech, Inc. β-Sheets and β-Hairpins: Molecular Recognition and Stability
April 4	CANCELLED Prof. Mark Hersam, Northwestern University Characterization and Manipulation of Individual Molecules on Semiconductor Surfaces
April 11	Prof. Paul Canfield, Iowa State University The Design, Growth, Discovery and Characterization of Novel Intermetallic Compounds
April 18	Prof. Jon Clardy, Harvard Medical School Discovering New Compounds in Nature
April 25	Prof. Héctor Abruña, Cornell University Nanometric Building Blocks and Devices

Fall 2005

September 6	Dr. Hans Bechtel, Massachusetts Institute of Technology Stretching and Bending the Bonds of Chemical Reactions
September 20	Prof. Samuel Gellman, University of Wisconsin, Madison Structure and Function in Foldamers
September 27	Prof. John Frost, Michigan State University Drugs, Energetic Materials, and Polymers: The Role of Microbial Catalysis
October 18	Prof. Seth Cohen, University of California, San Diego Novel Metalloligands for Heterometallic, Chiral Metal-Organic Frameworks
October 25	Dr. Stephen Baxter, Oblon, Spivak, McClelland, Maier & Neustadt, PC Chemical Patents
November 04	Prof. Ib Chorkendorff, Danmarks Teknikske Universitet Production and Conversion of Hydrogen on Alloys and Inorganic Compounds
November 08	Prof. Robert Westervelt, Harvard University Imaging a One-electron Quantum Dot using SPM
November 15	Prof. Craig Townsend, Johns Hopkins University Synthetic, Mechanistic and Engineering Studies of Unusual Biosynthetic Reactions
November 22	Prof. Carston Wagner, University of Minnesota Chemically Controlled Assembly of Protein Nanostructures
November 29	Prof. Anne Baranger, Wesleyan University Recognition of Single-Stranded RNA by Proteins and Small Molecules
December 08	Prof. Clemens Richert, Universität Karlsruhe Chemical Primer Extension

Spring 2005

January 18	Prof. Lawrence Que, Jr., University of Minnesota Oxygen Activation at Nonheme Iron.
February 01	Prof. Veronica Vaida, University of Colorado Atmospheric Organic Aerosols in Earth's Chemistry and Climate
February 08	Prof. Amit Basu, Brown University Glycolipid Interactions at Membranes: From Fundamental Studies of Adhesion to Lipopolysaccharide Sensors
February 15	Prof. Steven Baldelli, University of Houston Surface Spectroscopy of Room-Temperature Ionic Liquids at the Platinum-Liquid Electrochemical Interface
March 08	Prof. Claudia Steinem, Universität Regensburg Artificial Membranes: Tools to Address Biological Questions?
March 10	Prof. Andreas Janshoff, Johannes Gutenberg-Universität, Mainz Biosensors on the Microscale: From Biomimetic Surfaces to New Technologies Please Note Change in Day (Thursday)
March 29	Dr. Adrian Whitty, Biogen Idec Inc. Biochemistry on the Cell Membrane: A Quantitative View of Cytokine Receptor Activation Mechanisms
April 05	Prof. Paul Davidovits, Boston College Uptake of Gas Phase Species by Organic Liquids; The Strange Interactions of Gas Phase Hydrogen Halides with Octanol
April 12	Prof. Neil Marsh, University of Michigan A Radical Approach to Catalysis: Coenzyme B12 and Glutamate Mutase
April 14	Prof. James Mayer, University of Washington Oxidations of C-H and O-H Bonds by Metal Complexes: Hydrogen Atom Transfer, Proton-Coupled Electron Transfer, and Marcus Theory Please Note Change in Day (Thursday)
April 19	Prof. Gregory Weiss, University of California, Irvine Reverse Engineering Biomolecular Recognition with Combinatorial Protein Libraries
April 26	Hosted by Undergraduate Chapter of the ACS at Tufts Chemistry Dr. Michael Strem, Strem Chemicals, Inc. An Alternative Career Path: Starting and Running Your Own Chemical Company

Fall 2004

September 14	Prof. Linda Abriola, Tufts University, School of Engineering Micellar Solubilization of Chlorinated Solvents in Contaminated Formations : Process Design and Assessment of a Field Demonstration
September 21	Prof. Alan Kennan, Colorado State University Specific Control of Helical Peptide Self-assembly
September 28	Prof. Amy Mullin, Boston University Highly Excited Molecules: From "Supercollisions" to Super-Reactions
October 05	Prof. Stephen Kent, University of Chicago The Chemistry of Chemical Protein Synthesis: Methods & Targets
October 14	Prof. Dr. Kay Severin, Ecole polytechnique fédérale de Lausanne Synthesis of Catalysts and Receptors by Self-Assembly and Combinatorial Chemistry
October 19	Prof. Mark Meyerhoff, University of Michigan Nitric Oxide Releasing/Generating Polymers: Preparation, Characterization and Biomedical Applications
October 26	Prof. Joseph Sadighi, Massachusetts Institute of Technology Small Molecule Activation and New Bond-Forming Reactions by Low-Coordinate Late Transition Metal Complexes
November 02	Prof. Scott Strobel, Yale University Mechanism of RNA Catalyzed Splicing and Protein Synthesis
November 09	Prof. Suzanne Walker, Harvard Medical School Chemical Approaches to Understanding Bacterial Cell Wall Synthesis & its Inhibition
December 07	Prof. John Reif, Duke University Self-Assembled DNA Nanostructures for Molecular Scale Patterning, Computation and Motors

Spring 2004

February 03	Dr. Robert DiCosimo, DuPont Experimental Station Process Development Using Biocatalytic Nitrile Hydration and Hydrolysis
February 10	Prof. Shana Kelley, Boston College DNA Damage Promoted By Amino Acids
February 17	Prof. Charles Riordan, University of Delaware Nickel Coordination Chemistry: Biomimetic and Bioinspired Transformations
February 24	Prof. Dr. Michael Wolfe, Harvard Medical School Biochemistry and Inhibition of γ-Secretase
March 04	Prof. George Flynn, Columbia University STM Investigation of the Self-Assembly of Chiral and Achiral Molecules at Liquid-Solid and Solid- Vacuum Interfaces: Driving Forces for 2-D Separation and Organization of Molecules
March 11	Prof. Robert Langer, Massachusetts Institute of Technology Materials for Drug Delivery and Tissue Engineering
March 16	Prof. Jay Groves, University of California, Berkeley Molecular Pattern Formation and Signal Transduction at Intercellular Synapses
March 30	Dr. Steven Weissman, Merck Research Laboratories Practical Syntheses of Clinical Drug Candidates
April 06	Prof. Ian Harrison, University of Virginia C-H Bond Activation of Methane at Metal Surfaces: Several Ways...
April 14	Prof. Jiri Janata, Georgia Institute of Technology "Chemical Plume Tracing - How do Crabs do it?
April 15	Prof. Nadrian Seeman, New York University Structural DNA Nanotechnology
April 20	Prof. Stephen Kent, University of Chicago The Chemistry of Chemical Protein Synthesis: Methods & Targets
April 27	Prof. Brian Gibney, Columbia University On the Role of Nonnatural Amino Acid Ligands in De Novo Heme Protein Design
May 04	Dr. Raji Heyrovska, J. Heyrovsky Inst. of Phys. Chem. Simple Quantitative Thermodynamics of Electrolyte Solutions Based on Solvation and Partial Dissociation - A Centennial Tribute to Arrhenius

Fall 2003

September 09	Prof. Linda McGown, Duke University On-the-Fly Fluorescence Lifetime Detection in Capillary Electrophoresis: Genomic and Environmental Applications
September 16	Prof. Sean Elliott, Boston University Moving Electrons Through Enzymes
September 23	Prof. Ronald Raines, University of Wisconsin, Madison Stereoelectronic Effects on Protein Structure and Stability
October 07	Prof. Sylvia Daunert, University of Kentucky Achieving The Whole Through Integration: Genetic Engineering Strategies in Biosensing and Micro/Nanoanalytical Methods
October 09	Hosted by Undergraduate Chapter of the ACS at Tufts Chemistry Dr. Carl Selavka, Massachusetts State Police Crime Laboratory Why Forensic Science is Sexy; and Why You Shouldn't Trust CSI
October 14	Prof. Jillian Buriak, University of Alberta CANCELLED
October 21	Prof. Nadrian Seeman, New York University Structural DNA Nanotechnology
October 28	Prof. William Jones, University of Rochester Strong C-X Bond Cleavage Reactions Using Homogeneous Transition Metal Complexes
November 25	Prof. Kenneth Eisenthal, Columbia University Molecules at Liquid Surfaces
December 2	Prof. Terry Sheppard, Northwestern University Chemical Biology of DNA Damage and Chemoselective DNA Decoration

Spring 2003

January 21	Prof. William Reiff, Northeastern University On the Complex Magnetism of Seemingly Simple Dimers: From Disappearing Hyperfine Effects to Cooperative Long Range Order to Quantum Tunneling of Magnetization
January 28	Prof. Stephen Lippard, Massachusetts Institute of Technology Non-Heme Iron and the Biological Oxidation of Methane
February 4	Prof. Christopher Arumainayagam, Wellesley College Electron-Induced Reactions in Nanoscale Thin Films
February 11	Prof. James McKnight, Boston University Cross-Examining a Villin: Structure, Function and Folding of a Small F-Actin-Binding Domain
February 18	Prof. Linda McGown, Duke University DNA Aptamers in Proteomic Analysis
February 25	Dr. Russell Petter, Biogen, Inc. Remarkably Potent Antagonists of Integrin VLA-4
March 4	Prof. Barry Karger, Northeastern University New Technologies for Genomics and Proteomics Based on High Resolution Electrophoresis and Chromatography
March 13	Prof. Robert Walker, University of Maryland Solvation at Surfaces: Profiling Interfacial Solvent Polarity with Molecular Rulers
April 1	Prof. Chaitan Khosla, Stanford University Chemistry and Biology of Celiac Sprue
April 15	Hosted jointly by Electrochemical Society NE and Tufts Chemistry Prof. Heidi Martin, Case Western Reserve University Diamond-based Electrodes as Neurochemical Sensors
April 22	Prof. Hicham Fenniri, Purdue University Rosette Nanotubes: New Materials with Unprecedented Properties
May 13	Hosted jointly by Electrochemical Society NE and Tufts Chemistry Prof. Allen J Bard, University of Texas, Austin Application of Scanning Electrochemical Microscopy in High Resolution Investigation of Interfaces
June 13	Prof. Kazuya Kikuchi, University of Tokyo, Japan Design, Synthesis and ACellular Application of Chemical Probes, Which Convert Biological Responses to Chemical Output

Fall 2002

September 10	Prof. Howard Fairbrother, Johns Hopkins University Environmental/Atmospheric Chemistry at Surfaces and in Thin Films
September 17	Prof. James Nowick, University of California, Irvine Molecular Recognition Between b-Sheets in Proteins and in Model Systems
September 24	Hosted by the Undergraduate Chapter of the ACS at Tufts Dr. Richard Newman, Museum of Fine Arts, Boston The Real and Unreal: How Science Helps to Authenticate Works of Art
October 1	Dr. Daniel Auerbach, IBM Almaden Research Center Chemistry with Stretched Molecules: Using Vibrational Excitation to Probe Surface Chemical Dynamics
October 8	Prof. Andrew Ellington, University of Texas at Austin Evolution and Design of Nucleic Acid Biosensors
October 18	Prof. Dev Arya, Clemson University What's New With Neomycin?
October 22	Prof. Howard Mayne, University of New Hampshire Very Cold but Very Floppy Molecules: Structure and Reactions of Mixed Van Der Waals Atomic Clusters
October 29	Prof. Shahriar Mobashery, Wayne State University Antibacterials as Wonder Drugs and How Their Effectiveness Is Being Compromised
November 5	Prof. John Oliver, Brown University Universal Bases as Wild Cards for Sequencing by Hybridization

Spring 2002

Jan 22	Prof. John P. Toscano, Johns Hopkins University Rational Design of Novel Photochemical Precursors to Nitric Oxide
Feb 12	Prof. Andrei Tokmakoff, Massachusetts Institute of Technology Molecular Structure and Dynamics in Solution Observed Through Two-Dimensional Infrared Spectroscopy
Feb 19	Prof. Seiichi Matsuda, Rice University Tinkering with Terpene Biosynthesis
Feb 21	Hosted by the Undergraduate Chapter of the ACS at Tufts Dr. Mukund Chorghade, Geltex Pharmaceuticals, Inc. Progress of a Drug from Conception to Commercialization
Feb 26	Prof. John T. Groves, Princeton University The Chemistry and Biology of Peroxynitrite: Reactive, Invasive and Enigmatic
Mar 05	Prof. John A. Gerlt, University of Illinois, Urbana-Champaign Does Sequence or Structure Determine Enzyme Function? Different Reactions Catalyzed by the “Same” Active Site
Mar 12	Prof. Eric Bakker, Auburn University From Extremely Selective Ion Sensore to Smart Microspheres
Mar 26	Prof. Milan Mrksich, University of Chicago A Surface Chemistry Approach to Studying Cell Adhesion
Apr 5	Prof. Dr. Geert-Jan Kroes, Univerity of Leiden Vibrational Effects on Dissociative Chemisorption of Hydrogen on Cu(100) and Pt(111)
Apr 9	Prof. Lawrence Scott, Boston College Strategies for the Rational Synthesis of Fullerenes and Their Open Geodesic Siblings
Apr 16	Consensus Pharmaceuticals Lecture Prof. Julius Rebek, Jr., The Scripps Research Institute & The Skaggs Insititute for Chemical Biology Molecular Assembly and Encapsulation
Apr 23	Prof. Kenneth Karlin, Johns Hopkins University Synthetic Modeling of Copper and Heme-Copper Protein Dioxygen Chemistry

Fall 2001

Sep 04	Prof. Henry White, University of Utah – 5 PM seminar Electrochemical Imaging of Iontophoretic Transport Across Skin
Sep 11	Prof. James Canary, New York University Triggered Sterochemistry in Copper/Tripodal Ligand Compleses: Chirality Switches and Sensors
Sep 18	Prof. Melissa Hines, Cornell University In Search of Perfection: Using STM to Study Silicon Etching Reactions
Sep 25	To be scheduled
Oct 02	Prof. Peter Seeberger, Massachusetts Institute of Technology Automated Synthesis of Oligosaccharides: New Chemistry To Address Fundamental Biomedical Questions
Oct 16	Prof. Catherine Drennan, Massachusetts Institute of Technology When Bigger Isn’t Better: Crystal Structure of Class II Ribonucleotide Reductase
Oct 23	Prof. Peter Lansbury, Jr. Harvard Medical School and Brigham and Women’s Hospital The Emergence of New Therapeutic Targets for Parkinson’s Disease
Oct 30	Prof. Andrei Tokmakoff, Massachusetts Institute of Technology Molecular Structure and Dynamics in Solution Observed Through Two- Dimensional Infrared Spectroscopy
Nov 06	Prof. David Nesbitt, University of Colorado Radicals, Single Collisions and Single Molecules
Dec 04	Prof. Charles M. Drain, Hunter College of CUNY Self-assembly of Nanoscaled Photonic Materials

Spring 2001

Jan 23

Prof. Sergiu Gorun, Brown University

Artificial Enzymes: From Reversible Dioxygen Binding to Bioinspired Catalysis and Cancer Therapy

Jan 30

Prof. Catherine Drennan, Massachusetts Institute of Technology

B12-Dependent Ribonucleotide Reductase: Paradox or Paradigm

Feb 06

Dr. Lincoln Lauhon, Harvard University

Excitation and Chemical Manipulation of Single Hydrogen Atoms with a STM

Feb 13

Consensus Pharmaceuticals Lecture

Prof. Alanna Schepartz, Yale University

Functional Miniature Proteins

Feb 16

Prof. Dr. Hans-Joachim Galla, University of Münster

The Alveolar Surfactant: Only Half a Membrane but Indispensable for the Breathing Process

Feb 20

Prof. Mario Molina, Massachusetts Institute of Technology

From Local to Global Pollution: The Impact of Human Activities on Atmospheric Ozone (note time change – 5pm)

Feb 27

Prof. Tom Muir, Rockefeller University

Protein Ligation: Linking Chemistry and Biology one Peptide Bond at a Time

Mar 06

Prof. David Nesbitt, University of Colorado

Radicals, Single Collisions and Single Molecules

Mar 20

Prof. Jack Norton, Columbia University

Dynamic Asymmetric Transformation of Zirconaaziridines with an Optically Active Co₂ Synthon. Synthesis of Amino Acid Esters

Mar 29

Prof. Jeffery Kelly, The Scripps Research Institute & The Skaggs Institute for Chemical Biology

Understanding and Developing Therapeutic Strategies for Human Amyloid Diseases

Apr 03

Prof. Vincent Rotello, University of Massachusetts, Amherst

Polymers, Nanoparticles and Molecular Recognition. From ‘Plug and Play’ to ‘Bricks and Mortar’

Apr 10

Prof. Barbara Imperiali, Massachusetts Institute of Technology

Chemistry and Biology of Asparagine-Linked Protein Glycosylation

Apr 24

Prof. Michael Maroney, University of Massachusetts, Amherst

Structure and Function in Metalloenzymes: A Nickel Tour

Fall 2000

September 12	Prof. Gregory Petsko, Brandeis University The Trouble with Hydrogens
September 19	Prof. John Warner, University of Massachusetts, Boston Pollution Prevention using Molecular Recognition and Self Assembly: An Example of Green Chemistry
September 26	Prof. John Tully, Yale University Chemical Dynamics at Surfaces
October 3	Prof. Jeffrey Roberts, University of Minnesota Chemistry at a High-Traffic Interface: Uptake of Small Organic Molecules by Liquid Sulfuric Acid
October 17	Prof. James Rusling, University of Connecticut Active Biomolecular Films on Electrodes
October 24	Prof. Sean Decatur, Mount Holyoke College Probing Peptide Conformation and Dynamics via Isotope-Edited Infrared Spectroscopy
October 31	Prof. Sanford Asher, University of Pittsburgh Crystalline Colloidal Array Materials: Chemical Sensors and Electrooptical Applications
November 7	CANCELED Prof. Mario Molina, MIT
November 14	Prof. Robert Corn, University of Wisconsin, Madison DNA Computing at Surfaces
November 16	Prof. Dermot Diamond, Dublin City University From Synthesis to Signal Processing - Towards Autonomous Sensing Systems
November 21	Dr. David Casebier, Arqule Combinatorial Chemistry Applied to Lead Optimization: Numbers are Not Enough
November 28	Prof. Ricardo Metz, University of Massachusetts, Amherst Photofragment Spectroscopy of Reaction Intermediates and Multiply Charged Ions
December 5	Prof. Judith Herzfeld, Brandeis University Recapturing the Conceptual Core of General Chemistry

Spring 2000

January 25	Prof. Christoph Rose-Petruck, Brown University Ultrafast X-ray diffraction and X-ray absorption spectroscopy: Emerging new methods for observing the motions of atoms on the time scale of molecular vibrations
February 1	Prof. Sylvia Ceyer, MIT New surface reaction mechanisms: role of bulk H in catalytic hydrogenation and F atom abstraction by Si
February 8	Prof. Joseph Piccirilli, University of Chicago Mechanisms of RNA Catalysis Revealed by Chemically Modified Nucleic Acids
February 22	Prof. John Caradonna, Boston University Probing Old Metalloprotein Active Sites with New Proteins: The Same but Better....?
February 29	Prof. Scott Miller, Boston College Discovery of Minimal Peptides for Asymmetric Catalysis and Organic Synthesis
March 7	Prof. Smita Patel, University of Medicine and Dentistry of New Jersey Steps Towards Understanding the Mechanism of DNA Unwinding
April 4	Prof. Dinshaw Patel, Sloan-Kettering Institute Structural Basis of Adaptive Recognition by Nucleic Acid Aptamers
April 11	Prof. William Armstrong, Boston College A Synthetic Model Approach to Understanding the Photosystem II Water Oxidase Active Site
May 9	Prof. Francis Johnson, SUNY - Stony Brook (CANCELLED) The Artificial Creation of Naturally-Occurring DNA Damage

Fall 1999

September 14	Dr. George Gassner, MIT
	Mechanistic Studies of the Soluble Methane Monooxygenase System from M. capsulatus (Bath)

September 21	Prof. Stewart Novick, Wesleyan University
	Laboratory Astrochemistry: The Spectroscopy of Radicals

September 28	Prof. Thomas Bell, University of Nevada Reno
	Synthetic Receptors and Chemosensors for Biomolecules

Rational Design of Novel Photochemical Precursors to Nitric Oxide

Tinkering with Terpene Biosynthesis

Progress of a Drug from Conception to Commercialization

The Chemistry and Biology of Peroxynitrite: Reactive, Invasive and Enigmatic

From Extremely Selective Ion Sensore to Smart Microspheres

A Surface Chemistry Approach to Studying Cell Adhesion

Molecular Assembly and Encapsulation

Synthetic Modeling of Copper and Heme-Copper Protein Dioxygen Chemistry

Electrochemical Imaging of Iontophoretic Transport Across Skin

In Search of Perfection: Using STM to Study Silicon Etching Reactions

The Emergence of New Therapeutic Targets for Parkinson’s Disease

Radicals, Single Collisions and Single Molecules

Self-assembly of Nanoscaled Photonic Materials

B12-Dependent Ribonucleotide Reductase: Paradox or Paradigm

Excitation and Chemical Manipulation of Single Hydrogen Atoms with a STM

Functional Miniature Proteins

Protein Ligation: Linking Chemistry and Biology one Peptide Bond at a Time

Radicals, Single Collisions and Single Molecules

Chemistry and Biology of Asparagine-Linked Protein Glycosylation