David J. Wilbur

Department of Chemistry
Pearson Chemistry Laboratory
62 Talbot Avenue
Tufts University 
Medford, MA 02155 

Tel: ................. Fax: .................


>Departmental Instrumentation

Current Appointment






Postdoctoral Position 1974-1976, Indiana University

Ph.D. 1974, University of Illinois

B.S. 1969, University of Rochester



Tufts Chemistry Department (May 1999-present): Responsible for user training and maintenance of all shared research and teaching instrumentation in the Department. Periodically runs training sessions for NMR, mass spectrometry, and SEM, and provides informal training on other instruments as needed. Authored a number of training manuals for major instruments, and brief instructions for operating many of the smaller instruments. Instrumentation link above leads to an online tour of Department instrumentation, operating instructions, and a list of links to web sites devoted to chemical instrumentation.


Manager, Physics Engineering (1994-1999) Caprius, Inc., Wilmington, MA

Applications Specialist, NMR (1990-1993) Analogic Corp, Peabody, MA

Test Engineering Manager (1984-1990) Varian NMR Instruments, Palo Alto, CA

NMR Lab Manager (1983-1984) Stanford University, Palo Alto, CA


Selected Publications

Larry K. Keefer, Joseph A. Hrabie, Bruce D. Hilton, and David Wilbur.  Nitrogen Protonation of N-Nitrosomethylamine. J. Amer. Chem. Soc.110, 7459 1988.


Gariepy, Jean; Lane, Andrew; Frayman, Felix; Wilbur, David; Robien, Wolfgang; Schoolnik, Gary K.; Jardetzky, Oleg.  Structure of the toxic domain of Escherichia coli heat-stable enterotoxin ST I.    Biochemistry, 25(24), 7854-66 1986.


David Wilbur, Wayne B. Manning, Bruce D. Hilton, and Gary Muscik. Carbon-13 NMR of Polycyclic Aromatic Compounds. 1-Methoxybenz(a)anthracene-7,12-diones. Org. Magn. Resonance 18, 63 1982.


David H. Sieh, David J. Wilbur, and Christopher J. Michejda. Preparation of Trialkyltriazenes from Alkyl Azides. A Comparison of the N-N Bond Rotation in Trialkyltriazenes and Aryldialkyltriazenes by Variable Temperature C-13 NMR. J. Amer. Chem. Soc. 102, 3883 1980.


Wayne B. Manning and David J. Wilbur. Isolation and Structure of the Oxidized Diels-Alder Adducts of Certain Styrenes and 1,4-Napthoquinone. J. Org. Chem. 45, 733 1980.


Haleem J. Issaq, Mario M. Mangino, George M. Singer, David J. Wilbur, and Nelson H. Risser. Effect of Temperature on the Separation of Conformational Isomers of Nitrosamines by Thin Layer Chromatography. Anal. Chem. 51, 2157 1980.


David J. Wilbur, Carol Williams, and Adam Allerhand. Detection of the Furanose Anomers of D-Mannose in Aqueous Solution. Application of C-13 NMR Spectroscopy at 68 MHz. J. Amer. Chem. Soc. 99, 5450 1977.


David J. Wilbur and Adam Allerhand. Study of the Titration Behavior of N-Terminal Glycine Residues of Myoglobins by Natural Abundance C-13 NMR Spectroscopy. FEBS Lett. 79, 144 1977.


D. J. Wilbur and A. Allerhand. Titration Behavior and Tautomeric States of Individual Histidine Residues of Myoglobins. Application of Natural Abundance C-13 NMR Spectroscopy. J. Biol. Chem. 252, 4968 1977.


David J. Wilbur and Adam Allerhand. Observation of  -N-Trimethyllysine Residues of Proteins by Natural Abundance C-13 NMR Spectroscopy. FEBS Lett. 74, 272 1977.


David J. Wilbur, Raymond S. Norton, Arthur O. Clouse, Robert Addelman, and Adam Allerhand. Determination of Rotational Correlation Times of Proteins in Solution from C-13 Relaxation Measurements. Effect of Magnetic Field Strength and Anisotropic Rotation. J. Amer. Chem. Soc. 98, 8250 1976.


David J. Wilbur and Adam Allerhand. Titration Behavior of Individual Tyrosine Residues of Myoglobins from Sperm Whale, Horse, and Red Kangaroo. Application of Natural Abundance C-13 NMR Spectroscopy. J. Biol. Chem. 251, 5187 1976.


D. J. Wilbur, T. DeFreis and J. Jonas. Self-Diffusion in Compressed Liquid  Heavy Water. J. Chem. Phys. 65, 1783 1976.


J. Jonas, T. DeFreis and D. J. Wilbur. Molecular Motions in Compressed  Liquid Water. J. Chem. Phys. 65, 582 1976.


D. J. Wilbur and J. Jonas. Fourier Transform NMR at High Pressure. III.  Spin-Lattice Relaxation in Toluene D-8. J. Chem. Phys. 62, 2800 1975.


D. J. Wilbur and J. Jonas. Fourier Transform NMR at High Pressure. II. F-19 Chemical Shift in Benzotriflourides. J. Magn. Reson. 10, 279 1973.


D. J. Wilbur and J. Jonas. NMR Fourier Transform NMR at High Pressures. J. Chem. Phys. 55, 5840 1971.


D. Wilbur and R. Kreilick. Nitroxide Radical- Metal Chelate Interactions. J. Chem. Phys. 52, 1643 1970.


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