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Tufts Chemistry

 

Undergraduate Only (CHEM 0001-0092)  

0001 Chemical Fundamentals.  Atomic and molecular structure; intermolecular forces and states of matter; the relation of structure and bonding to the physical and chemical properties of matter; patterns of chemical reactions. Qualitative thermodynamics and equilibrium. Three lectures, one laboratory, one recitation. Only one of Chemistry 1, 11, or 16 may be counted for credit.  

0002 Chemical Principles.  Physical and chemical equilibria, properties of solutions, thermochemistry and thermodynamics. Chemistry of selected elements. The laboratory includes preparative inorganic chemistry. Additional topics may include electrochemistry, nuclear chemistry, coordination chemistry, organic chemistry, polymer chemistry, biochemistry. Three lectures, one laboratory, one recitation. Prerequisite: Chemistry 1, 11, 16, or consent. Only one of Chemistry 2 or 12 may be counted for credit. 

0008 Environmental Chemistry. An introductory course designed primarily to give nonscience majors an appreciation of basic chemical principles underlying the causes of and possible solutions to current environmental problems. The concept of equilibrium in complex systems; thermodynamic limits and kinetic realities. Case studies from current literature. Prerequisite: High-school chemistry. Spring 2000 and alternate years.  

0011, 0012 General Chemistry. Topics covered are the same as in Chemistry 1 and 2, but discussed in greater detail and with a higher degree of mathematical rigor. Designed to provide a strong foundation for advanced courses in chemistry. For well-prepared students intending to be science majors. Some familiarity with elementary calculus concepts assumed. Three lectures, one seminar on frontiers in chemistry, one laboratory, one recitation. Three courses. Prerequisites: Score of at least 3 on the AP chemistry exam or consent; Mathematics 11 (may be taken concurrently). Only one of Chemistry 1, 11, or 16 and one of Chemistry 2 or 12 may be counted for credit.  

0016 Chemistry of Materials.  An introductory course investigating the fundamentals and principles of chemistry through exploration of modern materials, e.g., thin films, superconductors, ultrasmall structures, modern electronics and photonics. Topics include atomic and molecular structure, intermolecular forces, ionic and covalent bonding. This one-semester course may be used in conjunction with Chemistry 2 to fulfill the basic chemistry requirement for a chemistry major. Three lectures, one recitation, one laboratory. Prerequisite: Good background in mathematics. Only one of Chemistry 1, 11, or 16 may be counted for credit. 

0031 Physical Chemistry I.   Fundamental principles of chemical thermodynamics and kinetics and their application to the energetics and rates of chemical reactions in the gaseous and solution states. Three lectures. Prerequisites: Chemistry 2 or 12, Mathematics 12 or equivalent, and Physics 2, 4, or 12, or consent. (Physics may be taken concurrently.) Fall. 

0032 Physical Chemistry II. Four main topics of modern physical chemistry: elementary wave mechanics and chemical bonding, elementary statistical thermodynamics, elementary mathematical models for problems in molecular structure, topics in chemical kinetics. Three lectures. Prerequisites: Chemistry 2 or 12, Mathematics 12, and Physics 2, 4, or 12, or consent. Spring 

0033 Beginning Physical Chemistry Laboratory. Thermodynamic, kinetic, and electrochemical experiments. One laboratory. One-half course. Prerequisites: Chemistry 31 or concurrent registration. Fall.

0034 Intermediate Physical Chemistry Laboratory. Spectroscopic, kinetic, and advanced physical-chemistry experiments. One laboratory. One-half course. Prerequisites: Chemistry 32 or concurrent registration. Spring

0042 Analytical Chemistry.   Introduction to methods of quantitative analysis including, error & statistical analyses, data treatment, basic instrumental concepts of electroanalysis, spectroscopy, and chromatography.  For both chemistry and life science majors, as well as students enrolled in environmental studies. Three lectures, two laboratories. One and one-half courses. Prerequisite: Chemistry 2, 12, or consent. Spring 

0050 Survey of Organic Chemistry.  One semester survey of organic chemistry. Topics include structure and bonding in organic molecules, spectroscopy, stereochemistry, reactivity, synthesis, polymer chemistry, and bioorganic chemistry. Will not fulfill the organic chemistry requirement for chemistry majors, premedical, predental, or preveterinary students. May not be taken for credit in conjunction with Chemistry 51 or 52. Students needing a laboratory should register for Chemistry 53. Three lectures. Prerequisite: Chemistry 2 or 12.   

0051 Organic Chemistry I  Structure, bonding, stereochemistry, and reactions of carbon compounds. Mono- and polyfunctional compounds, aliphatic and aromatic structures. Synthesis, reaction mechanisms, electronic interpretations of reactivity, spectroscopy. Two 75-minute lectures, one recitation. One course. (Note: The laboratory course, Chemistry 53, is normally taken concurrently with Chemistry 51.) Prerequisite: Chemistry 2 or 12. Fall. 

0052 Organic Chemistry II.  Continuation of the topics presented in Chemistry 51.  Two 75-minute lectures, one recitation.  One course.  (Note:  The laboratory course, Chemistry 54, is normally taken concurrently with Chemistry 52).  Prerequisite:  Chemistry 51. Spring

53 Organic Chemistry Laboratory I. Experiments based on topics in Chemistry 51. One laboratory, one lecture. One-half course. Co-requisite or prerequisite: Chemistry 50 or 51. Fall.

0054 Organic Chemistry Laboratory II.  Experiments based on topics in Chemistry 52. One laboratory, one lecture. One-half course. Prerequisite: Chemistry 53. Co-requisite or prerequisite: Chemistry 52. Spring.

0055 Advanced Synthesis Laboratory. Introduction to advanced laboratory techniques in synthetic organic and inorganic chemistry. Emphasis on synthetic methods that involve organometallics, catalysts, and enzymes. Techniques include inert atmosphere manipulations, chromatography, and spectroscopic analysis. Nine hours of laboratory. Prerequisites: Chemistry 52 and 54.  

0061 Inorganic Chemistry.  Chemistry illustrative of the kinds of bonding in inorganic compounds, including discussions of ionic, covalent, electron-deficient, and coordination compounds. Three lectures. Prerequisites: Chemistry 31 and 52. Only one of Chemistry 61 or 161 may be taken for credit.  Fall.

0063 Inorganic and Synthetic Chemistry Laboratory.  Experiments include those based on topics in Chemistry 61. Techniques in synthesis, spectroscopy, and reactivity studies. Applications of inorganic compounds in synthesis, catalysis, materials sciences, and biology. One laboratory, one lecture, one-half course. Prerequisites Chemistry 61 or 161. Fall

0091 Research I. Training in the methods of chemical research. Frequent conferences and library assignments. Open to qualified advanced students. At least fifteen hours per week of laboratory or research work in chemistry required. Prerequisite: consent. Pass-fail grading. 

0092 Research II. Continued training in the methods of research. At least fifteen hours per week of laboratory or other research work in chemistry required. Students write a report of research accomplished. Prerequisites: Chemistry 91 and consent.

 Undergraduate & Graduate (CHEM 0131-0194)

0131 Chemical Thermodynamics. A detailed application of the laws of thermodynamics to chemical and phase equilibria. Thermodynamics of solutions and solids. Introductory statistical thermodynamics. Three lectures. Prerequisites: Chemistry 31 and Mathematics 13, or consent. Spring 2006 and alternate years.

0132 Chemical Kinetics and Dynamics. Study of chemical reaction rates in the gas phase and solution. Topics include kinetic models, experimental methods, molecular reaction dynamics, kinetic theory of gases, potential energy surfaces, and transition state theory. Prerequisite: Chemistry 32 or consent. Spring 2007 and alternate years. 

0133 Quantum Mechanics. Covers Schrödinger equation and basic quantized systems, statistical interpretation and uncertainty, perturbation theory, scattering, symmetries and invariances, approximation methods, energy calculations. Prerequisite: Chemistry 32; Mathematics 38 recommended. Fall.

0134 Statistical Mechanics. Fermi-Dirac, Bose-Einstein, and Maxwell-Boltzmann statistics. Ensembles, most probable distribution, and fluctuations. Calculation of chemical potential from molecular constants; determination of equilibrium in gas-phase reaction systems; transport properties; simple theories of solids, liquids, and solution. Prerequisite: Chemistry 32; Mathematics 38 recommended. 

0135 Biophysical Chemistry. Thermodynamics of biochemical systems, biochemical and biological dynamics, biochemical spectroscopy and structure determination, statistical thermodynamics and transport properties, electrochemistry in the biological context, and membrane biophysics. Three lectures. Prerequisites: Chemistry 52 and 31.

0136 Spectroscopy and Molecular Structure. Electronic, vibrational, and rotational energy levels of molecules, and transitions between these levels. Molecular symmetry. Time dependence and symmetry requirements of spectroscopic transitions. Born-Oppenheimer approximation, Franck-Condon principle, potential surfaces, other spectroscopic methods. Prerequisite: Chemistry 133 or consent. Spring 2007 and alternate years. 

0141 Instrumental Analysis.   Theory, operation, and application of principal instruments used in chemical analysis and research. Selected special topics such as molecular, atomic, and mass spectroscopies; electrochemistry; and chromatography are included. Designed to acquaint the student with modern laboratory techniques used in all areas of chemistry. Prerequisites: Chemistry 31, 42, and 51, or consent. Fall.

0142 Advanced Analytical Methods.  Course Material for Fall 2007. In depth study of several modern specialized techniques and their application to current qualitative and quantitative problems in environmental, materials, and biochemical areas of analysis.  Prerequisites: Chemistry 42 or 141, or consent. Fall 2009

0144 Spectroscopic Methods of Analysis. Spectroscopic analytical techniques, including principles and applications of spectroscopic measurements, fundamental interaction of radiation and matter, emission spectroscopy, atomic absorption, UV-visible fluorescence, Fourier transform IR, X-ray techniques, mass spectroscopy, and surface techniques such as AES, ESCA, and SIMS. Three lectures. Prerequisites: Chemistry 42 or 141, or consent. Spring 2007 and alternate years.  

0145 Separation Science. Basic separation theory, practice, and instrumentation in gas, liquid, and other chromatographies, membrane and affinity separations, extraction techniques, electrophoresis, and separations based on phase equilibria. Three lectures. Prerequisites: Chemistry 42 or 141, or consent. Spring 2008 and alternate years.   

0146 Electroanalytical Chemistry.  Basic theory and application of modern electrochemical methods of analysis including potentiometry, amperometry, voltammetry, modern cyclic/pulse techniques, and stripping analysis. Mechanisms, kinetics, and electron transfer theory may also be covered. Prerequisites: Chemistry 42 or consent. Fall 2010  

0150 Intermediate Organic Chemistry.  Survey of the principles of organic chemistry. Topics include reaction mechanisms, synthesis, and spectroscopic methods of structure determination. Three lectures. Prerequisite: Chemistry 52. Fall.  

0151 Physical Organic Chemistry. Advanced organic chemistry with emphasis on structure and reaction mechanisms, uses of kinetics and other physical methods, and dynamic interaction between current theoretical concepts and experiment. Three lectures. Prerequisite: Chemistry 52. Spring 2006 and alternate years.  

0152 Advanced Organic Synthesis. Study of noteworthy syntheses of complex molecules with a view to developing a rationale and methodology for synthesis. Examination of the mechanism and scope of new bond-forming methods and functional group transformations. Three lectures. Prerequisite: Chemistry 52. Spring 2007 and alternate years.  

0155 Organic Spectroscopy. Applications of NMR, IR, UV, and mass spectrometry to the identification of organic compounds. Three class meetings. Prerequisite: Chemistry 52.

0157 Medicinal Chemistry. Molecular-level mechanism of action of compounds useful in human medicine. Introduces the biochemistry of a biological system relevant to a particular disease process, then focuses on the detailed interaction of chemotherapeutic agents with the system. Material is drawn principally from the primary literature. Course is not comprehensive. Topics may include antiviral/antitumor agents, compounds affecting immunity and inflammation, antibiotics, nucleic-acid-based therapeutics, and combinatorial drug discovery methods. Prerequisites: Biology 13 and Chemistry 52. Spring 2006 and alternate years.  

0161 Advanced Inorganic Chemistry. Atomic and molecular structure. Symmetry operations and symmetry point groups. Chemical bonding in inorganic and coordination compounds. Types of inorganic reactions and their mechanisms. Reactivity of major classes of inorganic compounds. Descriptive chemistry of selected main-group elements. More rigorous than Chemistry 61. May receive credit for only one of Chemistry 61 or 161. Prerequisites: Chemistry 32 and 52. Fall.  

0162 Chemistry of Transition Elements. Descriptive and theoretical chemistry of transition elements; structure, bonding, reactivity, and spectroscopic properties of metal complexes. Prerequisite: Chemistry 61 or 161. Spring 2007 and alternate years. Members of the Department

0163 Diffraction Methods of Structure Determination.  Introduction to structure determination methods that give detailed information on atomic arrangements in crystalline solids. Emphasis on single-crystal X-ray diffraction, with some attention to neutron diffraction, and powder methods. Space group symmetry, structure factors, methods of structure solution, and measures of structure accuracy. Prerequisite: consent. Spring 2007  

0164 Bioinorganic Chemistry. The role of metal ions in living organisms; understanding and modeling. Metal ion transport and storage, biocoordination chemistry of ion pumps. Metal ion folding and cross-linking of biomolecules. Small molecule (oxygen, nitrogen) binding and activation. Hydrolytic and redox metalloenzymes. Structure-function relationships in metalloenzyme mimics. Bioinorganic chemistry and drug design. Prerequisite: Chemistry 61 or 161, or consent. Fall 2006 and alternate years.  

0165 Physical Methods in Inorganic Chemistry. Spectroscopic methods in inorganic and coordination chemistry: UV-Vis, infrared, Raman, electron paramagnetic resonance, nuclear quadrupole resonance, Mossbauer spectroscopy. Multinuclear NMR, NMR of paramagnetic compounds. Magnetism applications of different methods to electronic structure determination and to studies on complexation in solution. X-ray crystallography. Prerequisite: Chemistry 61 or 161, or consent. Spring 2006,

0170 Scientific Writing. A writing laboratory based on scientific material encountered in current chemical research, with a focus on the writing and preparation of scientific manuscripts. One-half course. Prerequisite: consent. .  

0171 Biochemistry I.  First course in a two-course sequence. Chemistry of biological molecules: proteins, lipids, carbohydrates, nucleic acids, etc. Mechanisms of enzyme and ribozyme catalysis. Metabolic pathways, integrated metabolic systems, and molecular physiology. Co-listed as BIO 171. One course. Prerequisites: BIO 13, CHEM 52. Fall. Members of the faculty of the Chemistry and Biology Departments.

0172 Biochemistry II.  Second course in a two-course sequence. Chemistry of biological molecules: proteins, lipids, carbohydrates, nucleic acids, etc. Mechanisms of enzyme and ribozyme catalysis. Metabolic pathways, integrated metabolic systems, and molecular physiology. Co-listed as BIO 172. One course. Prerequisites: CHEM 171. Spring. View Team Biochem skit from Spring 2006

0191, 0192 Seminar in Chemistry. Discussion of specialized problems and current chemical research. Prerequisite: open to qualified advanced students in chemistry. Credit as arranged. Required for all first year graduate students.  Outside Speakers

0193, 0194 Special Topics. Guided individual study of an approved topic. Credit as arranged. Members of the Department

Graduate Only (CHEM 0237-0502)

0237, 0238 Special Topics in Physical Chemistry. Selected topics of contemporary interest in physical chemistry. Three lectures. Prerequisite: consent. Two courses. 

0247, 0248 Special Topics in Analytical Chemistry.  Selected topics of contemporary interest in analytical and instrumental chemistry. Three lectures. Prerequisite: consent. Two courses.  

0257, 0258 Special Topics in Organic Chemistry.  Selected topics of contemporary interest in organic chemistry. Three lectures. Prerequisite: consent. Two courses. 

0267, 0268 Special Topics in Inorganic Chemistry. Selected topics of contemporary interest in inorganic chemistry. Three lectures. Prerequisite: consent. Two courses. 

0293, 0294 Special Topics. Guided individual study of an approved topic. Credit as arranged. 

0295, 0296 Thesis. Guided research on a topic that has been approved as a suitable subject for a master's thesis. Credit as arranged.

0297, 0298 Graduate Research. Guided research on a topic suitable for a doctoral dissertation. Credit as arranged.

0401PT Master's Continuation, Part-time.

0402FT Master's Continuation, Full-time.

0501PT Doctoral Continuation, Part-time.

0502FT Doctoral Continuation, Full-time.

 

05/09/08