Only (CHEM 0001-0092)
0001 Chemical Fundamentals
with Lab. Atomic and molecular structure,
intermolecular forces and states of matter, the relation
of structure and bonding to the physical and chemical
properties of matter, patterns of chemical reactions,
stoichiometry, and thermochemistry. Additional topics
may include qualitative thermodynamics and equilibrium
and chemistry of materials. Three lectures, one
laboratory, one recitation. Only one of Chemistry 1, 11,
or 16, may be counted for credit.
0002 Chemical Principles
with Lab. Properties of solutions, chemical
kinetics and thermodynamics, physical and chemical
equilibria, aqueous equilibria (acid-base,
precipitation, and complex formation), electrochemistry.
Additional topics may include environmental, nuclear,
and coordination chemistry, and chemistry of selected
elements. Three lectures, one laboratory, one
recitation. Prerequisite: Chemistry 1, 11, 16, or
consent. Only one of Chemistry 2 or 12 may be counted
0006 From the Big Bang to
Humankind. Course will explore the origins of
the Universe, the formation of Earth and its structure,
the chemistry of life, the development of complex
organisms, and the development of modern humans.
Students will learn the evidence for the various ideas
presented, the scientific method used by scientists, and
how the community of scientists evaluates the evidence.
This course does not fulfill pre-medical requirements
for a lab-based chemistry course.
Chemistry. An introductory course designed primarily
to give non-science majors an appreciation of basic chemical
principles underlying the causes of and possible solutions
to current environmental problems. The concept of equilibrium
in complex systems; thermodynamic limits and kinetic realities.
Case studies from current literature. Prerequisite: High-school
chemistry. Spring 2000 and alternate years.
General Chemistry. Topics covered are the same as
in Chemistry 1 and 2, but discussed in greater detail
and with a higher degree of mathematical rigor. Designed
to provide a strong foundation for advanced courses in
chemistry. For well-prepared students intending to be
science majors. Some familiarity with elementary calculus
concepts assumed. Three lectures, one seminar on frontiers
in chemistry, one laboratory, one recitation. Three courses.
Prerequisites: Score of at least 3 on the AP chemistry
exam or consent; Mathematics 32 (may be taken concurrently).
Only one of Chemistry 1, 11, or 16 and one of Chemistry
2 or 12 may be counted for credit.
of Materials. An introductory course investigating the fundamentals
and principles of chemistry through exploration of modern
materials, e.g., thin films, superconductors, ultrasmall
structures, modern electronics and photonics. Topics
include atomic and molecular structure, intermolecular
forces, ionic and covalent bonding. This one-semester
course may be used in conjunction with Chemistry 2 to
fulfill the basic chemistry requirement for a chemistry
major. Three lectures, one recitation, one laboratory.
Prerequisite: Good background in mathematics. Only one
of Chemistry 1, 11, or 16 may be counted for credit.
Chemistry I. Fundamental principles of chemical thermodynamics and
kinetics and their application to the energetics and rates
of chemical reactions in the gaseous and solution states.
Three lectures. Prerequisites: Chemistry 2 or 12, Mathematics
34 or equivalent, and Physics 2, 4, or 12, or consent.
(Physics may be taken concurrently.) Fall.
Chemistry II. Four main topics of modern physical
chemistry: elementary wave mechanics and chemical
bonding, elementary statistical thermodynamics,
elementary mathematical models for problems in molecular
structure, topics in chemical kinetics. Three lectures.
Prerequisites: Chemistry 2 or 12, Mathematics 34, and
Physics 2, 4, or 12, or consent. Spring
Physical Chemistry Laboratory. Thermodynamic, kinetic,
and electrochemical experiments. One laboratory. One-half
course. Prerequisites: Chemistry 31 or concurrent registration.
Physical Chemistry Laboratory. Spectroscopic, kinetic,
and advanced physical-chemistry experiments. One laboratory.
One-half course. Prerequisites: Chemistry 32 or concurrent
0042 Quantitative Analysis. Introduction to the methods and scientific basis of quantitative analysis including, sampling, error & statistical analyses, data treatment & presentation, basic concepts and operation of chromatographic, electroanalytical, and spectroscopic instrumentation. For chemistry and life science majors, as well as students enrolled in environmental studies and engineering. The course will provide students in chemistry or any related discipline with the necessary foundation, understanding, and basic tools for doing good science and operating common analytical instrumentation. Three lectures, two laboratories. One and one-half courses. Prerequisites: Chemistry 2 or 12. Spring.
0050 Survey of
Organic Chemistry. One semester survey of organic chemistry. Topics include
structure and bonding in organic molecules, spectroscopy,
stereochemistry, reactivity, synthesis, polymer chemistry,
and bioorganic chemistry. Will not fulfill the organic
chemistry requirement for chemistry majors, premedical,
pre-dental, or pre-veterinary students. May not be taken
for credit in conjunction with Chemistry 51 or 52.
Students needing a laboratory should register for
Chemistry 53. Three lectures. Prerequisite: Chemistry 2
0051 Organic Chemistry
Structure, bonding, conformational analysis, functional groups, and stereochemistry. Organic reactions, synthesis, and mechanisms including acid/base reactions, nucleophilic substitution and elimination, reactions of alcohols, ethers, aldehydes, ketones, carboxylic acids and their derivatives, and amines. Tools for structure determination including nuclear magnetic resonance and infrared spectroscopy. Two 75-minute lectures, one recitation. One course. (Note: The laboratory course, CHEM 53, is normally taken concurrently with CHEM 51.) Prerequisites: CHEM 2 or 12.
0052 Organic Chemistry
II. Continuation of CHEM 51. Structure, properties, and reactions of alkenes, alkynes, conjugated unsaturated systems and aromatic compounds. Radical reactions. Mechanisms, retrosynthetic analysis and synthetic strategy. Additional topics such as the chemistry of carbohydrates, lipids, amino acids, and nucleic acids. Two 75-minute lectures, one recitation. One course. (Note: The laboratory course, CHEM 54, is normally taken concurrently with CHEM 52.) Prerequisites: CHEM 51
0053 Organic Chemistry
Laboratory I. Experiments based on topics in Chemistry
51. One laboratory, one lecture. One-half course. Co-requisite
or prerequisite: Chemistry 50 or 51. Fall.
0054 Organic Chemistry
Laboratory II. Experiments based on topics in Chemistry 52. One laboratory,
one lecture. One-half course. Prerequisite: Chemistry
53. Co-requisite or prerequisite: Chemistry 52. Spring.
Synthesis Laboratory. Introduction to advanced laboratory
techniques in synthetic organic and inorganic chemistry.
Emphasis on synthetic methods that involve organometallics,
catalysts, and enzymes. Techniques include inert atmosphere
manipulations, chromatography, and spectroscopic analysis.
Nine hours of laboratory. Prerequisites: Chemistry 52
Chemistry. Chemistry illustrative of the kinds
of bonding in inorganic compounds, including discussions
of ionic, covalent, electron-deficient, and coordination
compounds. Three lectures. Prerequisites: Chemistry 31
and 52. Only one of Chemistry 61 or 161 may be taken for
and Synthetic Chemistry Laboratory.
Experiments include those based on
topics in Chemistry 61. Techniques in synthesis,
spectroscopy, and reactivity studies. Applications of
inorganic compounds in synthesis, catalysis, materials
sciences, and biology. One laboratory, one lecture,
one-half course. Prerequisites Chemistry 61 or 161. Fall
I. (Previously CHEM 91) Training in the methods of chemical research. Frequent conferences and library assignments. Open to qualified advanced students. Requires at least fifteen hours per week of laboratory and/or other research work in chemistry during the fall or spring semesters, or 35-40 hours per week during the summer sessions. Pass-fail grading.
II. (Previously CHEM 92) Continued training in the methods of research. Requires at least fifteen hours per week of laboratory and/or other research work in chemistry during the fall or spring semesters, or 35-40 hours per week during the summer sessions. Students write a report of research accomplished. Recommendations: CHEM 81 and permission of instructor.
III-VIII. Continued training in the methods of research. Requires at least fifteen hours per week of laboratory and/or other research work in chemistry during the fall or spring semesters, or 35-40 hours per week during the summer sessions. Students write a report of research accomplished. Recommendations: permission of instructor. Courses must be taken in numerical order, starting with CHEM 81. One-credit courses.
0094 Science & the Human Experience. For non-chemistry majors - does not count towards the chemistry undergraduate major.
Undergraduate & Graduate
Thermodynamics. A detailed application of the laws
of thermodynamics to chemical and phase equilibria. Thermodynamics
of solutions and solids. Introductory statistical thermodynamics.
Three lectures. Prerequisites: Chemistry 31 and Mathematics
42, or consent. Spring 2014 and alternate years.
Kinetics and Dynamics. Study of chemical reaction
rates in the gas phase and solution. Topics include kinetic
models, experimental methods, molecular reaction dynamics,
kinetic theory of gases, potential energy surfaces, and
transition state theory. Prerequisite: Chemistry 32 or
consent. Fall 2013 and alternate years.
Mechanics. Covers Schrödinger equation and basic quantized
systems, statistical interpretation and uncertainty, perturbation
theory, scattering, symmetries and invariance, approximation
methods, energy calculations. Prerequisite: Chemistry
32; Mathematics 51 recommended. Fall.
Mechanics. Fermi-Dirac, Bose-Einstein, and Maxwell-Boltzmann
statistics. Ensembles, most probable distribution, and
fluctuations. Calculation of chemical potential from molecular
constants; determination of equilibrium in gas-phase reaction
systems; transport properties; simple theories of solids,
liquids, and solution. Prerequisite: Chemistry 32; Mathematics
Chemistry. Thermodynamics of biochemical systems,
biochemical and biological dynamics, biochemical spectroscopy
and structure determination, statistical thermodynamics
and transport properties, electrochemistry in the biological
context, and membrane biophysics. Three lectures. Prerequisites:
Chemistry 52 and 31.
and Molecular Structure. Electronic, vibrational,
and rotational energy levels of molecules, and transitions
between these levels. Molecular symmetry. Time dependence
and symmetry requirements of spectroscopic transitions.
Born-Oppenheimer approximation, Franck-Condon principle,
potential surfaces, other spectroscopic methods. Prerequisite:
Chemistry 133 or consent. Spring 2013 and alternate years.
Analysis. Theory, operation,
and application of principal instruments used in chemical
analysis and research. Selected special topics such as
molecular, atomic, and mass spectroscopies; electrochemistry;
and chromatography are included. Designed to acquaint
the student with modern laboratory techniques used in
all areas of chemistry. Students will select an analytical project of their choosing (with instructor approval) incorporating analytical metrics of precision, accuracy, selectivity, and sensitvity as well as develop experiments and questions that relate theory to experimental data. Recommendations: Chemistry 31, 42,
and 51, or consent. Fall.
Analytical Methods. Student lead case studies of modern analytical
instrumentation and its application to
chemically-related problems in a broad variety of
research areas such as environmental, materials,
biomedical, and others. Course requires in-depth oral
and written presentations based on recently published
literature. Recommendations: Chemistry 42 or 141, or equivalent taken elsewhere, or
permission of instructor. Enrollment limited to 9 students. Spring 2017.
Methods of Analysis. Spectroscopic analytical techniques,
including principles and applications of spectroscopic
measurements, fundamental interaction of radiation and
matter, emission spectroscopy, atomic absorption, UV-visible
fluorescence, Fourier transform IR, X-ray techniques,
mass spectroscopy, and surface techniques such as AES,
ESCA, and SIMS. Three lectures. Recommendations: Chemistry
42 or 141, or consent. Spring 2018 and alternate years.
Science. Basic separation theory, practice, and instrumentation
in gas, liquid, and other chromatographies, membrane and
affinity separations, extraction techniques, electrophoresis,
and separations based on phase equilibria. Three lectures.
Recommendations: Chemistry 42 or 141, or consent. Spring
2017 and alternate years.
Chemistry. Basic theory and application
of modern electrochemical methods of analysis including
potentiometry, amperometry, voltammetry, modern
cyclic/pulse techniques, and stripping analysis.
Mechanisms, kinetics, and electron transfer theory may
also be covered. Recommendations: Chemistry 42 or consent.
Survey of the principles
of organic chemistry. Topics include reaction mechanisms,
synthesis, and spectroscopic methods of structure determination.
Three lectures. Prerequisite: Chemistry 52. Fall.
Organic Chemistry. Advanced organic chemistry with
emphasis on structure and reaction mechanisms, uses of
kinetics and other physical methods, and dynamic interaction
between current theoretical concepts and experiment. Three
lectures. Prerequisite: Chemistry 52. Fall 2015.
Organic Synthesis. Study of noteworthy syntheses of
complex molecules with a view to developing a rationale
and methodology for synthesis. Examination of the mechanism
and scope of new bond-forming methods and functional group
transformations. Three lectures. Prerequisite: Chemistry
Spectroscopy. Applications of NMR, IR, UV, and mass
spectrometry to the identification of organic compounds.
Three class meetings. Prerequisite: Chemistry 52.
Chemistry. Molecular-level mechanism of action of
compounds useful in human medicine. Introduces the biochemistry
of a biological system relevant to a particular disease
process, then focuses on the detailed interaction of chemotherapeutic
agents with the system. Material is drawn principally
from the primary literature. Course is not comprehensive.
Topics may include antiviral/antitumor agents, compounds
affecting immunity and inflammation, antibiotics, nucleic-acid-based
therapeutics, and combinatorial drug discovery methods.
Prerequisites: Biology 13 and Chemistry 52. Spring 2014
and alternate years.
Inorganic Chemistry. Atomic and molecular structure.
Symmetry operations and symmetry point groups. Chemical
bonding in inorganic and coordination compounds. Types
of inorganic reactions and their mechanisms. Reactivity
of major classes of inorganic compounds. Descriptive chemistry
of selected main-group elements. More rigorous than Chemistry
61. May receive credit for only one of Chemistry 61 or
161. Prerequisites: Chemistry 32 and 52. Fall.
of Transition Elements. Descriptive and theoretical
chemistry of transition elements; structure, bonding,
reactivity, and spectroscopic properties of metal complexes.
Prerequisite: Chemistry 61 or 161. Spring 2015 and alternate
years. Members of the Department
Methods of Structure Determination. Introduction
to structure determination methods that give detailed
information on atomic arrangements in crystalline solids.
Emphasis on single-crystal X-ray diffraction, with some
attention to neutron diffraction, and powder methods.
Space group symmetry, structure factors, methods of structure
solution, and measures of structure accuracy. Prerequisite:
Chemistry. The role of metal ions in living organisms;
understanding and modeling. Metal ion transport and storage,
biocoordination chemistry of ion pumps. Metal ion folding
and cross-linking of biomolecules. Small molecule (oxygen,
nitrogen) binding and activation. Hydrolytic and redox
metalloenzymes. Structure-function relationships in metalloenzyme
mimics. Bioinorganic chemistry and drug design. Prerequisite:
Chemistry 61 or 161, or consent. Fall 2006 and alternate
Methods in Inorganic Chemistry. Spectroscopic methods
in inorganic and coordination chemistry: UV-Vis, infrared,
Raman, electron paramagnetic resonance, nuclear quadrupole
resonance, Mossbauer spectroscopy. Multinuclear NMR, NMR
of paramagnetic compounds. Magnetism applications of different
methods to electronic structure determination and to studies
on complexation in solution. X-ray crystallography. Prerequisite:
Chemistry 61 or 161, or consent. Spring 2006
Writing. A writing laboratory based on scientific
material encountered in current chemical research, with
a focus on the writing and preparation of scientific manuscripts.
One-half course. Prerequisite: consent.
0171 Organic Chemistry of Living Systems: Biochemistry . Structure and function of proteins, nucleic acids, carbohydrates, and lipids. Mechanisms and molecular function of binding proteins, enzymes, and membrane transporters. In-depth explorations of metabolic pathways and regulation with connections to physiology and human disease. Prerequisites: Chemistry 51 or two semesters of organic chemistry taken elsewhere. Recommended Biology 13. Spring.
0172 Advanced Biochemistry. Understanding human health and disease at the molecular level. Synthesis and breakdown of carbohydrates, lipids, amino acids, nucleic acids, and proteins. Molecular understanding of human metabolism and cellular signaling. Special topics in modern biomedical science.
Prerequisite: Chemistry 171. Fall.
Seminar in Chemistry. Discussion of specialized problems
and current chemical research. Prerequisite: open to qualified
advanced students in chemistry. Credit as arranged.
Required for all first year graduate students. Invited Speakers
Special Topics. Guided individual study of an approved
topic. Credit as arranged. Members of the Department
Senior Thesis I. Intensive research investigation, to be combined with
Chemistry 0199 leading to a written thesis. At least 20
hours per week of research work is required. Application
is made during the sixth or at the start of the seventh
semester. One course credit. Prerequisites: At least one
summer or semester of research prior to the senior year,
senior standing as a major in chemistry, biochemistry,
ACS certified chemistry, or chemical physics, and
department approval. Fall
Senior Thesis II.
Continuation of Chemistry 0195, culminating in a written
thesis and oral defense. At least 20 hour per week of
research is required. One course credit. Prerequisites:
CHEM 195. Spring.
Graduate Only (CHEM
0237, 0238 Special
Topics in Physical Chemistry. Selected topics of contemporary
interest in physical chemistry. Three lectures. Prerequisite:
consent. Two courses.
0247, 0248 Special
Topics in Analytical Chemistry. Selected topics
of contemporary interest in analytical and instrumental
chemistry. Three lectures. Prerequisite: consent. Two
0257, 0258 Special
Topics in Organic Chemistry. Selected topics
of contemporary interest in organic chemistry. Three lectures.
Prerequisite: consent. Two courses.
0267, 0268 Special
Topics in Inorganic Chemistry. Selected topics of
contemporary interest in inorganic chemistry. Three lectures.
Prerequisite: consent. Two courses.
0291, 0292 Professional Skills in Chemical Research. Topics will include: joining a research group, scientific writing, public speaking, study topic and original proposal success, literature management, thesis preparation, research group specific safety, shipping of chemicals, public communication, careers in science, involvement the local scientific community, and outreach.
Prerequisites: Permission of instructor
0293, 0294 Special
Topics. Guided individual study of an approved topic.
Credit as arranged.
0295, 0296 Thesis. Guided research on a topic that has been approved as
a suitable subject for a master's thesis. Credit as
0297, 0298 Graduate
Research. Guided research on a topic suitable for a
doctoral dissertation. Credit as arranged.